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Ondansetron works to prevent nausea and vomiting by blocking serotonin at certain receptors in the body. It is much easier to prevent nausea and vomiting than to treat it once it starts. Ondansetron is licensed to prevent nausea and vomiting, but it is not a treatment for vomiting or nausea. Ondansetron Mylan ODT 4 mg and 8 mg tablets contain the following excipients: Microcrystalline cellulose, mannitol, pregelatinised maize starch, crospovidone, aspartame, guar gum, colloidal anhydrous silica, magnesium stearate, sodium lauryl sulphate, Strawberry Guarana 586997 AP0551 Ondansetron Mylan ODT 4 mg orally disintegrating tablets Size. TE Rating. Prescribing Info. Medication Guide.